The gamma ray is at the shortest wavelength of the electromagnetic spectrum and has the highest energy. It is massless, unloaded and spreads at the speed of light. They are ionizing rays. As they pass through matter, they can remove electrons from atoms or molecules. This results in electrically charged particles, ie ions. Gamma rays produce strong DNA damage, creating permanent DNA damage. In addition, free radicals resulting from ionization have an indirect microbicidal effect. Since gamma rays are high energy rays, their penetration power is very high. It can be used for sterilization of end products as it has the feature of passing through the package material. It is also a fast, effective and reliable method that can be applied to heat sensitive products that cannot be sterilized by conventional techniques such as steam sterilization. In some types of plastics, flexibility may decrease and brittleness may occur, and some products may change color. Gamma serialization is an easy method for traceability and validation. After the process, no residue or waste material is formed on the product. There is no ventilation requirement and no quarantine time.