Advantages and Disadvantages of Sterilization Methods

STERILIZATION METHOD	ADVANTAGES	DISADVANTAGES
Steam	Harmless to employees, patients and the environment. Easy to control and monitor Fast microbicidal effect Short cycle time Penetrating medical packages and lumen devices	Not suitable for heat sensitive materials
Hydrogen peroxide Gas sterilization	Harmless to healthcare workers and the environment It does not leave toxic residual Short cycle time Suitable for temperature and steam sensitive materials Easy to use Compatible with many medical materials	Not suitable for cellulose, cotton and liquids 40 cm length and 3 mm lumen diameter limitation Polypropylene packaging requirement and specific container requirement
EO	Good penetration into packed and luminous instruments Single dose cartridge Minimal gas leakage in negative pressure medium Easy to use Compatible with many medical supplies	Ventilation requirement for removal of EtO Toxic, Carcinogenic, Flammable, Explosive Ventilation time is long
Steam Formaldehyde at Low Temperature	Good penetration into packed and lumen instruments Easy to use Compatible with many medical supplies	Toxic, Carcinogen
Ozone	Provides sterilization No ventilation time Suitable for temperature and moisture sensitive materials No environmental damage Lumen penetration good	Liquids cannot be sterilized. Special packaging material is required. Not compatible with cellulose, latex, rubber, textile.

Kaynakça: Sterilizasyon Dezenfeksiyon Rehberi Temmuz, 2015
http://www.das.org.tr/dosya/DASRehber2015.pdf